What is SENACTIV®?

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When it comes to supporting joint health and mobility, SENACTIV® has emerged as a popular ingredient in dietary supplements. In this blog post, we will explore the details of SENACTIV®, including its origin, recommended dosage, and usage recommendations.

Origin of SENACTIV®

SENACTIV® is a proprietary blend developed by Gnosis by Lesaffre, a leading company specializing in innovative natural solutions. It is derived from Saccharomyces cerevisiae, a species of yeast commonly used in food production. The yeast undergoes a specialized fermentation process to obtain SENACTIV®, resulting in a concentrated form of specific compounds that support joint health.

Dosage Recommendations

The optimal dosage of SENACTIV® may vary depending on factors such as age, weight, individual needs, and specific product formulations. It is essential to follow the recommended dosage instructions provided by the supplement manufacturer. As a general guideline, a typical dosage range for SENACTIV® is around 300-500 mg per day.

However, it's important to note that specific dosage recommendations may differ based on the intended use and the concentration of SENACTIV® in the supplement formulation. Always consult the product label and consider professional advice from healthcare practitioners or experts familiar with your specific health condition.

Usage Recommendations

SENACTIV® is primarily used to support joint health, flexibility, and mobility. Here are some key usage recommendations to consider:

Consistency: To experience the potential benefits of SENACTIV®, it is essential to maintain consistent usage over time. Incorporating it into your daily routine and adhering to the recommended dosage is crucial for obtaining optimal results.

  1. Timing: SENACTIV® can be consumed at any time of the day, preferably with a meal. However, it is advisable to consult the supplement manufacturer's recommendations regarding timing, as they may suggest specific instructions for best absorption and effectiveness.
  2. Combination with Other Supplements: SENACTIV® can be used alongside other joint health supplements, such as glucosamine, chondroitin, or omega-3 fatty acids, for synergistic effects. However, it is important to consult with a healthcare professional or expert to ensure compatibility and avoid any potential interactions.
  3. Individual Response: As with any dietary supplement, individual response to SENACTIV® may vary. Some individuals may experience noticeable benefits within a few weeks, while others may require more extended usage to observe significant improvements in joint health and mobility. Patience and consistent usage are key.
  4. Consultation with Healthcare Professionals: If you have any underlying health conditions, are taking medications, or are pregnant or breastfeeding, it is crucial to consult with a healthcare professional before starting any new supplement regimen, including SENACTIV®.


SENACTIV®, derived from Saccharomyces cerevisiae yeast through a specialized fermentation process, is a proprietary blend known for supporting joint health and mobility. By understanding its origin, recommended dosage, and usage recommendations, individuals can make informed decisions about incorporating SENACTIV® into their daily routine to support their joint health goals.

Always follow the recommended dosage provided by the supplement manufacturer and consult with healthcare professionals or experts to ensure compatibility with your specific health condition. Remember that dietary supplements should complement a healthy lifestyle that includes regular exercise, a balanced diet, and maintaining a healthy weight.

By incorporating SENACTIV® and embracing a holistic approach to joint health, you can optimize your joint mobility and support an active, fulfilling lifestyle.

SENACTIV® Claims and Research

 Publications can be found in The Journal of Ginseng Research, PLOS One, AgingJournal of Functional Foods, and many more of the top scientific journals in the country. A short list of significant results that the clinicals have demonstrated is showcased below. 

  • Increase muscle recovery by glycogen synthesis by 273%.
  • Increase endurance performance at high exercise intensity by 20%
  • Increase energy levels by increasing citrate synthase by 47% 
  • Decrease muscle damage marker: creatine kinase by 69% 
  • Reduce free radical damage to muscle after exercise (MDA synthesis stress) by 44% 
  • Reduces inflammation by decreasing IL-6 Synthesis, and pro-inflammatory cytokine by 35% 
  • Decrease sarcolemma lipid peroxidation by 68%
  • Reduces lipid peroxidation marker TBARS by 24%
  • Elimination of senescent cells in exercising human skeletal muscle
  • Reduction of stem cell aging in human skeletal muscle
  • Recruitment of new satellite cell production 


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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